Haplotype frequencies are a crucial input for registries using search algorithms to identify a matching unrelated donor for hematopoietic stem cell transplantation. Recently, DKMS expanded the typing profile for newly registered donors to include HLA-DPA1, -DQA1, -DRB3, -DRB4, and -DRB5 besides HLA-A, -B, -C, -DRB1, -DQB1, -DPB1, -E and the major histocompatibility complex (MHC) class I chain-related genes A (MICA) and B (MICB).