Nanopore sequencing revolutionizes genetic analysis by utilizing nanopore technology to obtain high resolution results at the same price.
Nanopore sequencing is a novel technology with several advantages for HLA genotyping. Its longer read length completely eliminates the problem of phasing ambiguities and offers a higher resolution for the same price. Therefore, we constantly evaluate the newest developments of flowcells and chemistries for GridION, MinION and PromethION instruments (Oxford Nanopore Technologies) and develop a nanopore specific analysis pipeline for HLA genotyping (Klasberg et al., 2019).