In Acute Lymphoblastic Leukemia (ALL), Measurable Residual Disease (MRD) is the best predictor of outcome and is used to direct risk-stratified therapy. HemaTrackTM ALL is a robust, highly accurate, and economical MRD assay based on next generation sequencing (NGS) technology.
DKMS Life Science Lab India is bringing a molecular, DNA-based MRD diagnostic method for ALL patients with a maximum level of sensitivity at an affordable price to cancer hospitals in India.
Dilution experiment demonstrates the sensitivity of HemaTrackTM ALL
In this experiment, DNA extracted from the cell line 'REH' with known clonotype identities was diluted with DNA extracted from a healthy donor (NC - negative control) to investigate the alignment of HemaTrackTM ALL to the ground truth in an artificial setting with known clonotype frequencies. In this dilution series, the clonotype frequencies measured by HemaTrackTM correlate impressively with the ground truth (expected clonotype frequency). HemaTrackTM ALL accurately quantifies clonotype frequencies up to a dilution of 8*10-5.
Retrospective study (completed)
Prospective studies (ongoing)
Multi Centre Prospective Study (from Q1 2025)
If you are interested in the results of the studies, send us your contact details via contact form.
Dr Anindita Dutta
Head of Lab Strategy and Operations
DKMS Life Science Lab Pvt. Ltd.
is an subsidiary of the non-profit organization DKMS Life Science Lab in Germany.
We aim to support the DKMS in the fight against blood cancer and other diseases of the hematopoietic system. We contribute to the improvement of treatment options through the best possible patient diagnostics services to save the lives of as many patients as possible.